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</ul> </div> </div> </div> </header> <div class="top-bar"> <div class="container"> <header class="page-header"> <h1 class="page-title"><span class="vcard">Claudia Filozof, M.D., Ph.D.</span></h1> </header><!-- .page-header --> <div class="breadcrumb-wrapper"> <div id="crumbs" itemscope itemtype="http://schema.org/BreadcrumbList"> <span itemprop="itemListElement" itemscope itemtype="http://schema.org/ListItem"> <a itemprop="item" href="https://ddblog.labcorp.com"><span itemprop="name">Home</span></a> <meta itemprop="position" content="1" /> <span class="separator">/</span> </span><span class="current" itemprop="itemListElement" itemscope itemtype="http://schema.org/ListItem"><a itemprop="item" href="https://ddblog.labcorp.com/author/claudia-filozof/"><span itemprop="name">Claudia Filozof, M.D., Ph.D.</span></a><meta itemprop="position" content="2" /></span></div></div><!-- .breadcrumb-wrapper --> </div> </div> <div class="container main-content"> <div id="content" class="site-content"> <div class="row"> <div id="primary" class="content-area"> <main id="main" class="site-main"> <div class="row"> <article id="post-2706" class="post-2706 post type-post status-publish format-standard has-post-thumbnail hentry category-clinical-development category-drug-development tag-cancer tag-nash latest_post" itemscope itemtype="https://schema.org/Blog"> <a href="https://ddblog.labcorp.com/2016/04/clinical-outcomes-nash-choosing-right-endpoints/" class="post-thumbnail"><img width="400" height="300" src="https://ddblog.labcorp.com/wp-content/uploads/2016/04/NASH-Article-Covance-BLOG.jpg" class="attachment-blossom-feminine-cat size-blossom-feminine-cat wp-post-image" alt="Clinical Outcomes in NASH" srcset="https://ddblog.labcorp.com/wp-content/uploads/2016/04/NASH-Article-Covance-BLOG.jpg 5000w, https://ddblog.labcorp.com/wp-content/uploads/2016/04/NASH-Article-Covance-BLOG-300x225.jpg 300w, https://ddblog.labcorp.com/wp-content/uploads/2016/04/NASH-Article-Covance-BLOG-768x576.jpg 768w, https://ddblog.labcorp.com/wp-content/uploads/2016/04/NASH-Article-Covance-BLOG-1024x768.jpg 1024w, https://ddblog.labcorp.com/wp-content/uploads/2016/04/NASH-Article-Covance-BLOG-400x300.jpg 400w" sizes="(max-width: 400px) 100vw, 400px" data-attachment-id="2707" data-permalink="https://ddblog.labcorp.com/2016/04/clinical-outcomes-nash-choosing-right-endpoints/nash-article-covance-blog/" data-orig-file="https://ddblog.labcorp.com/wp-content/uploads/2016/04/NASH-Article-Covance-BLOG.jpg" data-orig-size="5000,3750" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="NASH Article Covance BLOG" data-image-description="<p>Clinical Outcomes in NASH Covance Blog</p> " data-medium-file="https://ddblog.labcorp.com/wp-content/uploads/2016/04/NASH-Article-Covance-BLOG-300x225.jpg" data-large-file="https://ddblog.labcorp.com/wp-content/uploads/2016/04/NASH-Article-Covance-BLOG-1024x768.jpg" /></a> <div class="text-holder"> <header class="entry-header"> <div class="top"> <div class="share"> <i class="fa fa-share-alt"></i>Share <div class="social-networks"> <ul> <li><a href="https://www.linkedin.com/shareArticle?mini=true&url=https://ddblog.labcorp.com/2016/04/clinical-outcomes-nash-choosing-right-endpoints/&title=Clinical%20Outcomes%20in%20NASH:%20Choosing%20the%20Right%20Endpoints" rel="nofollow" target="_blank"><i class="fa fa-linkedin" aria-hidden="true"></i></a></li><li><a href="https://twitter.com/home?status=Clinical%20Outcomes%20in%20NASH:%20Choosing%20the%20Right%20Endpoints https://ddblog.labcorp.com/2016/04/clinical-outcomes-nash-choosing-right-endpoints/" rel="nofollow" target="_blank"><i class="fa fa-twitter" aria-hidden="true"></i></a></li><li><a href="https://www.facebook.com/sharer/sharer.php?u=https://ddblog.labcorp.com/2016/04/clinical-outcomes-nash-choosing-right-endpoints/" rel="nofollow" target="_blank"><i class="fa fa-facebook" aria-hidden="true"></i></a></li><li><a href="/cdn-cgi/l/email-protection#754a2600171f1016014836191c1b1c1614195047453a0001161a1810065047451c1b5047453b34263d4f504745361d1a1a061c1b12504745011d10504745271c121d01504745301b11051a1c1b0106535645464d4e371a110c481d010105064f5a5a111117191a125b191417161a07055b161a185a474544435a45415a16191c1b1c161419581a0001161a181006581b14061d58161d1a1a061c1b1258071c121d0158101b11051a1c1b01065a" rel="nofollow" target="_blank"><i class="fa fa-envelope" aria-hidden="true"></i></a></li> </ul> </div> </div> </div><h2 class="entry-title" itemprop="headline"><a href="https://ddblog.labcorp.com/2016/04/clinical-outcomes-nash-choosing-right-endpoints/" rel="bookmark">Clinical Outcomes in NASH: Choosing the Right Endpoints</a></h2><div class="entry-meta"><span class="byline" itemprop="author" itemscope itemtype="https://schema.org/Person"> by <span class="author vcard" itemprop="name"><a class="url fn n" href="https://ddblog.labcorp.com/author/claudia-filozof/">Claudia Filozof, M.D., Ph.D.</a></span></span><span class="posted-on"><span class="text-on">updated on </span><a href="https://ddblog.labcorp.com/2016/04/clinical-outcomes-nash-choosing-right-endpoints/" rel="bookmark"><time class="entry-date published updated" datetime="2021-05-19T12:50:39-04:00" itemprop="dateModified">Wednesday, May 19, 2021</time><time class="updated" datetime="2016-04-27T08:43:11-04:00" itemprop="datePublished">Wednesday, April 27, 2016</time></a></span></div><!-- .entry-meta --> </header><!-- .entry-header home--> <div class="entry-content" itemprop="text"> <p>Non-alcoholic steatohepatitis (NASH) can lead to serious conditions such as cirrhosis and its complications, liver cancer and hepatic transplantation. Many patients eventually die from liver-related problems or cardiovascular disease. The challenge in developing drugs for NASH is to demonstrate an improvement in clinical outcomes. Cirrhosis takes several years to develop, … </p> </div><!-- .entry-content --> <footer class="entry-footer"> </footer><!-- .entry-footer home--> </div><!-- .text-holder --> </article><!-- #post-2706 --> </div> <div class="pagination"></div> </main><!-- #main --> </div><!-- #primary --> </div><!-- .row/not-found --> </div><!-- #content --> </div><!-- .container/.main-content --> <footer id="colophon" class="site-footer" itemscope itemtype="http://schema.org/WPFooter"> <div class="site-info"> <div class="container"> <span class="copyright">Copyright © 2022 Labcorp All rights reserved.</span> </div> </div> </footer><!-- #colophon --> <button aria-label="go to top" id="blossom-top"> <span><i class="fa fa-angle-up"></i>TOP</span> </button> </div><!-- #page --> <script data-cfasync="false" src="/cdn-cgi/scripts/5c5dd728/cloudflare-static/email-decode.min.js"></script><script type='text/javascript' src='https://ddblog.labcorp.com/wp-content/themes/blossom-feminine-pro/js/all.min.js?ver=5.6.3'></script> <script type='text/javascript' src='https://ddblog.labcorp.com/wp-content/themes/blossom-feminine-pro/js/v4-shims.min.js?ver=5.6.3'></script> <script type='text/javascript' src='https://ddblog.labcorp.com/wp-content/themes/blossom-feminine-pro/js/sticky-kit.min.js?ver=1.1.3'></script> <script type='text/javascript' src='https://ddblog.labcorp.com/wp-content/themes/blossom-feminine-pro/js/owl.carousel.min.js?ver=2.2.1'></script> <script type='text/javascript' src='https://ddblog.labcorp.com/wp-content/themes/blossom-feminine-pro/js/owl.carousel.aria.min.js?ver=2.0.0'></script> <script type='text/javascript' src='https://ddblog.labcorp.com/wp-content/themes/blossom-feminine-pro/js/jquery.matchHeight.min.js?ver=0.7.2'></script> <script type='text/javascript' src='https://ddblog.labcorp.com/wp-content/themes/blossom-feminine-pro/js/wow.min.js?ver=1.1.3'></script> <script type='text/javascript'> /* <![CDATA[ */ var bfp_data = {"lightbox":"","auto":"","loop":"","speed":"3000","animation":"fadeOut","child":"default","sticky":"","sticky_widget":"","header":"eight","url":"https:\/\/ddblog.labcorp.com\/wp-admin\/admin-ajax.php","rtl":""}; /* ]]> */ </script> <script type='text/javascript' src='https://ddblog.labcorp.com/wp-content/themes/blossom-feminine-pro/js/custom.min.js?ver=2.3.3'></script> <script type='text/javascript'> /* <![CDATA[ */ var bfp_ajax = {"url":"https:\/\/ddblog.labcorp.com\/wp-admin\/admin-ajax.php","startPage":"1","maxPages":"1","nextLink":null,"autoLoad":"load_more","loadmore":"Load More Posts","loading":"Loading...","nomore":"No More Post","layouts":"two-col-right","plugin_url":"https:\/\/ddblog.labcorp.com\/wp-content\/plugins"}; /* ]]> */ </script> <script type='text/javascript' src='https://ddblog.labcorp.com/wp-content/themes/blossom-feminine-pro/js/ajax.min.js?ver=2.3.3'></script> <script type='text/javascript' src='https://ddblog.labcorp.com/wp-includes/js/wp-embed.min.js?ver=5.4'></script> <script type='text/javascript'> /* <![CDATA[ */ var jetpackCarouselStrings = {"widths":[370,700,1000,1200,1400,2000],"is_logged_in":"","lang":"en","ajaxurl":"https:\/\/ddblog.labcorp.com\/wp-admin\/admin-ajax.php","nonce":"fb8858bdae","display_exif":"1","display_comments":"1","display_geo":"1","single_image_gallery":"1","single_image_gallery_media_file":"","background_color":"black","comment":"Comment","post_comment":"Post Comment","write_comment":"Write a Comment...","loading_comments":"Loading Comments...","download_original":"View full size <span class=\"photo-size\">{0}<span class=\"photo-size-times\">\u00d7<\/span>{1}<\/span>","no_comment_text":"Please be sure to submit some text with your comment.","no_comment_email":"Please provide an email address to comment.","no_comment_author":"Please provide your name to comment.","comment_post_error":"Sorry, but there was an error posting your comment. 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