</ iframe></noscript> <!-- End Google Tag Manager (noscript) --> <div id="page" class="site"><a aria-label="skip to content" class="skip-link" href="#content">Skip to Content</a> <header class="site-header header-layout-three header-layout-seven header-layout-eight" itemscope itemtype="http://schema.org/WPHeader"> <div class="header-holder"> <div class="header-m" style="background-image:url(https://ddblog.labcorp.com/wp-content/uploads/2021/07/blog-header-1.png)"> <div class="container"> <div class="site-branding" itemscope itemtype="http://schema.org/Organization"> <p class="site-title" itemprop="name"><a href="https://ddblog.labcorp.com/" rel="home" itemprop="url">Insights From Our Labs to Yours</a></p> <p class="site-description" itemprop="description">Labcorp Drug Development Blog</p> </div> </div> </div> </div> <div class="sticky-holder"></div> <div class="header-b"> <div class="container"> <button aria-label="primary menu toggle" id="primary-toggle-button"><i class="fa fa-bars"></i>Navigation</button> <nav id="site-navigation" class="main-navigation" itemscope itemtype="http://schema.org/SiteNavigationElement"> <div class="menu-main-container"><ul id="primary-menu" class="menu"><li id="menu-item-6077" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-home menu-item-6077"><a href="https://ddblog.labcorp.com">Home</a></li> <li id="menu-item-5821" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-has-children menu-item-5821"><a href="https://ddblog.labcorp.com/industry/">Industry</a> <ul class="sub-menu"> <li id="menu-item-5824" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-5824"><a href="https://ddblog.labcorp.com/industry/device/">Device</a></li> <li id="menu-item-5825" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-5825"><a href="https://ddblog.labcorp.com/industry/drug-development/">Drug</a></li> <li id="menu-item-5822" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-5822"><a href="https://ddblog.labcorp.com/industry/chemical/">Chemical</a></li> <li id="menu-item-5823" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-5823"><a href="https://ddblog.labcorp.com/industry/crop/">Crop</a></li> </ul> </li> <li id="menu-item-5828" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-has-children menu-item-5828"><a href="https://ddblog.labcorp.com/phase/">Phase</a> <ul class="sub-menu"> <li id="menu-item-5829" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-5829"><a href="https://ddblog.labcorp.com/phase/discovery/">Discovery</a></li> <li id="menu-item-5835" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-5835"><a href="https://ddblog.labcorp.com/phase/preclinical-nonclinical/">Preclinical/Nonclinical</a></li> <li id="menu-item-5831" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-5831"><a href="https://ddblog.labcorp.com/phase/phase-i-iia/">Phase I-IIa</a></li> <li id="menu-item-5832" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-5832"><a href="https://ddblog.labcorp.com/phase/phase-iib-iii/">Phase IIb-III</a></li> <li id="menu-item-5833" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-5833"><a href="https://ddblog.labcorp.com/phase/pilot/">Pilot</a></li> <li id="menu-item-5834" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-5834"><a href="https://ddblog.labcorp.com/phase/pivotal/">Pivotal</a></li> <li id="menu-item-5830" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-5830"><a href="https://ddblog.labcorp.com/phase/formulation-packaging/">Formulation, Packaging, etc.</a></li> </ul> </li> <li id="menu-item-5836" class="menu-item menu-item-type-taxonomy menu-item-object-category current-category-ancestor current-menu-ancestor current-menu-parent current-category-parent menu-item-has-children menu-item-5836"><a href="https://ddblog.labcorp.com/molecule-type/">Molecule Type</a> <ul class="sub-menu"> <li id="menu-item-5837" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-5837"><a href="https://ddblog.labcorp.com/molecule-type/biologics/">Biologics</a></li> <li id="menu-item-5841" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-5841"><a href="https://ddblog.labcorp.com/molecule-type/small-molecules/">Small Molecules</a></li> <li id="menu-item-5839" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-5839"><a href="https://ddblog.labcorp.com/molecule-type/biosimilars/">Biosimilars</a></li> <li id="menu-item-5838" class="menu-item menu-item-type-taxonomy menu-item-object-category current-menu-item menu-item-5838"><a href="https://ddblog.labcorp.com/molecule-type/biomarkers/" aria-current="page">Biomarkers</a></li> <li id="menu-item-5840" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-5840"><a href="https://ddblog.labcorp.com/molecule-type/cell-gene-therapies/">Cell/Gene Therapies</a></li> </ul> </li> <li id="menu-item-5844" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-has-children menu-item-5844"><a href="https://ddblog.labcorp.com/data-informatics/">Data/Informatics</a> <ul class="sub-menu"> <li id="menu-item-5842" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-5842"><a href="https://ddblog.labcorp.com/data-informatics/send/">SEND</a></li> <li id="menu-item-5845" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-5845"><a href="https://ddblog.labcorp.com/data-informatics/modeling/">Modeling</a></li> <li id="menu-item-5846" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-5846"><a href="https://ddblog.labcorp.com/data-informatics/patient-recruitment/">Patient Recruitment</a></li> <li id="menu-item-5843" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-5843"><a href="https://ddblog.labcorp.com/data-informatics/xcellerate/">Xcellerate</a></li> </ul> </li> <li id="menu-item-5827" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-has-children menu-item-5827"><a href="https://ddblog.labcorp.com/about-covance/">About Us</a> <ul class="sub-menu"> <li id="menu-item-5704" class="menu-item menu-item-type-taxonomy menu-item-object-category menu-item-5704"><a href="https://ddblog.labcorp.com/about-covance/careers-and-culture/">Careers and Culture</a></li> <li id="menu-item-5792" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-5792"><a href="http://response.covance.com/contact-us?elqCampaignId=399&cid=Web_Clk_CVD_blog_megamenunav_0615_399">Contact Us</a></li> <li id="menu-item-5791" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-5791"><a href="https://drugdevelopment.labcorp.com">Labcorp Drug Development</a></li> </ul> </li> </ul></div> </nav><!-- #site-navigation --> <div class="right"> <div class="tools"> <div class="form-section"> <button aria-label="search form toggle" id="btn-search"><i class="fa fa-search"></i></button> <div class="form-holder"> <form role="search" method="get" class="search-form" action="https://ddblog.labcorp.com/"> <label> <span class="screen-reader-text">Search for:</span> <input type="search" class="search-field" placeholder="Search …" value="" name="s" /> </label> <input type="submit" class="search-submit" value="Search" /> </form> </div> </div> </div> <ul class="social-networks"> <li><a href="https://www.linkedin.com/company/labcorpdrugdevelopment" target="_blank" rel="nofollow"><i class="fab fa-linkedin"></i></a></li> <li><a href="https://twitter.com/LabcorpDrugDev" target="_blank" rel="nofollow"><i class="fab fa-twitter-square"></i></a></li> <li><a href="https://www.facebook.com/LabcorpDrugDevelopment" target="_blank" rel="nofollow"><i class="fab fa-facebook"></i></a></li> </ul> </div> </div> </div> </header> <div class="top-bar"> <div class="container"> <header class="page-header"> <h1 class="page-title">Biomarkers</h1> </header><!-- .page-header --> <div class="breadcrumb-wrapper"> <div id="crumbs" itemscope itemtype="http://schema.org/BreadcrumbList"> <span itemprop="itemListElement" itemscope itemtype="http://schema.org/ListItem"> <a itemprop="item" href="https://ddblog.labcorp.com"><span itemprop="name">Home</span></a> <meta itemprop="position" content="1" /> <span class="separator">/</span> </span> <span itemprop="itemListElement" itemscope itemtype="http://schema.org/ListItem"><a itemprop="item" href="https://ddblog.labcorp.com/molecule-type/"><span itemprop="name">Molecule Type </span></a><meta itemprop="position" content="2" /><span class="separator">/</span></span> <span class="current" itemprop="itemListElement" itemscope itemtype="http://schema.org/ListItem"> <a itemprop="item" href="https://ddblog.labcorp.com/molecule-type/biomarkers/"><span itemprop="name">Biomarkers</span></a><meta itemprop="position" content="3" /> </span></div></div><!-- .breadcrumb-wrapper --> </div> </div> <div class="container main-content"> <div id="content" class="site-content"> <div class="row"> <div id="primary" class="content-area"> <main id="main" class="site-main"> <div class="row"> <article id="post-7655" class="post-7655 post type-post status-publish format-standard has-post-thumbnail hentry category-biomarkers category-drug-development category-oncology category-preclinical-nonclinical latest_post" itemscope itemtype="https://schema.org/Blog"> <a href="https://ddblog.labcorp.com/2020/12/accelerating-drug-development-timelines-evolution-in-trial-design-approaches-in-oncology/" class="post-thumbnail"><img width="450" height="300" src="https://ddblog.labcorp.com/wp-content/uploads/2020/12/Wearable-Devices-450x300.jpg" class="attachment-blossom-feminine-cat size-blossom-feminine-cat wp-post-image" alt="time" srcset="https://ddblog.labcorp.com/wp-content/uploads/2020/12/Wearable-Devices-450x300.jpg 450w, https://ddblog.labcorp.com/wp-content/uploads/2020/12/Wearable-Devices-300x200.jpg 300w, https://ddblog.labcorp.com/wp-content/uploads/2020/12/Wearable-Devices-1024x682.jpg 1024w, https://ddblog.labcorp.com/wp-content/uploads/2020/12/Wearable-Devices-768x511.jpg 768w, https://ddblog.labcorp.com/wp-content/uploads/2020/12/Wearable-Devices-1536x1023.jpg 1536w, https://ddblog.labcorp.com/wp-content/uploads/2020/12/Wearable-Devices-90x60.jpg 90w, https://ddblog.labcorp.com/wp-content/uploads/2020/12/Wearable-Devices.jpg 1679w" sizes="(max-width: 450px) 100vw, 450px" data-attachment-id="7656" data-permalink="https://ddblog.labcorp.com/2020/12/accelerating-drug-development-timelines-evolution-in-trial-design-approaches-in-oncology/56240943-blue-jacket-man-use-the-smart-watch-2/" data-orig-file="https://ddblog.labcorp.com/wp-content/uploads/2020/12/Wearable-Devices.jpg" data-orig-size="1679,1118" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"56240943 - blue jacket man use the smart watch.","created_timestamp":"0","copyright":"sheeler\/123RF","focal_length":"0","iso":"0","shutter_speed":"0","title":"56240943 - blue jacket man use the smart watch.","orientation":"0"}" data-image-title="" data-image-description="" data-medium-file="https://ddblog.labcorp.com/wp-content/uploads/2020/12/Wearable-Devices-300x200.jpg" data-large-file="https://ddblog.labcorp.com/wp-content/uploads/2020/12/Wearable-Devices-1024x682.jpg" /></a> <div class="text-holder"> <header class="entry-header"> <div class="top"> <div class="share"> <i class="fa fa-share-alt"></i>Share <div class="social-networks"> <ul> <li><a href="https://www.linkedin.com/shareArticle?mini=true&url=https://ddblog.labcorp.com/2020/12/accelerating-drug-development-timelines-evolution-in-trial-design-approaches-in-oncology/&title=Accelerating%20drug%20development%20timelines%20–%20Evolution%20in%20trial%20design%20approaches%20in%20oncology" rel="nofollow" target="_blank"><i class="fa fa-linkedin" aria-hidden="true"></i></a></li><li><a href="https://twitter.com/home?status=Accelerating%20drug%20development%20timelines%20–%20Evolution%20in%20trial%20design%20approaches%20in%20oncology https://ddblog.labcorp.com/2020/12/accelerating-drug-development-timelines-evolution-in-trial-design-approaches-in-oncology/" rel="nofollow" target="_blank"><i class="fa fa-twitter" aria-hidden="true"></i></a></li><li><a href="https://www.facebook.com/sharer/sharer.php?u=https://ddblog.labcorp.com/2020/12/accelerating-drug-development-timelines-evolution-in-trial-design-approaches-in-oncology/" rel="nofollow" target="_blank"><i class="fa fa-facebook" aria-hidden="true"></i></a></li><li><a href="/cdn-cgi/l/email-protection#c8f79bbdaaa2adabbcf589ababada4adbaa9bca1a6afedfaf8acbabdafedfaf8acadbeada4a7b8a5ada6bcedfaf8bca1a5ada4a1a6adbbedfaf8eeebf0faf9f9f3edfaf88dbea7a4bdbca1a7a6edfaf8a1a6edfaf8bcbaa1a9a4edfaf8acadbba1afa6edfaf8a9b8b8baa7a9aba0adbbedfaf8a1a6edfaf8a7a6aba7a4a7afb1eeebf8fbf0f38aa7acb1f5a0bcbcb8bbf2e7e7acacaaa4a7afe6a4a9aaaba7bab8e6aba7a5e7faf8faf8e7f9fae7a9ababada4adbaa9bca1a6afe5acbabdafe5acadbeada4a7b8a5ada6bce5bca1a5ada4a1a6adbbe5adbea7a4bdbca1a7a6e5a1a6e5bcbaa1a9a4e5acadbba1afa6e5a9b8b8baa7a9aba0adbbe5a1a6e5a7a6aba7a4a7afb1e7" rel="nofollow" target="_blank"><i class="fa fa-envelope" aria-hidden="true"></i></a></li> </ul> </div> </div> </div><h2 class="entry-title" itemprop="headline"><a href="https://ddblog.labcorp.com/2020/12/accelerating-drug-development-timelines-evolution-in-trial-design-approaches-in-oncology/" rel="bookmark">Accelerating drug development timelines – Evolution in trial design approaches in oncology</a></h2><div class="entry-meta"><span class="byline" itemprop="author" itemscope itemtype="https://schema.org/Person"> by <span class="author vcard" itemprop="name"><a class="url fn n" href="https://ddblog.labcorp.com/author/covance/">Labcorp Drug Development</a></span></span><span class="posted-on"><span class="text-on">updated on </span><a href="https://ddblog.labcorp.com/2020/12/accelerating-drug-development-timelines-evolution-in-trial-design-approaches-in-oncology/" rel="bookmark"><time class="entry-date published updated" datetime="2021-06-24T12:26:02-04:00" itemprop="dateModified">Thursday, June 24, 2021</time><time class="updated" datetime="2020-12-22T16:09:39-05:00" itemprop="datePublished">Tuesday, December 22, 2020</time></a></span></div><!-- .entry-meta --> </header><!-- .entry-header home--> <div class="entry-content" itemprop="text"> <p>Three specialists – Dr. Sarah Blagden, Associate Professor of Medical Oncology, University of Oxford; Maria Prendes, Head of Oncology at the Biomarker Solution Center; and Kamal Saini, Senior Medical Director of Oncology at Labcorp Drug Development – recently discussed this highly relevant topic in an educational webinar, which is now … </p> </div><!-- .entry-content --> <footer class="entry-footer"> </footer><!-- .entry-footer home--> </div><!-- .text-holder --> </article><!-- #post-7655 --> <article id="post-6096" class="post-6096 post type-post status-publish format-standard has-post-thumbnail hentry category-biomarkers category-drug-development tag-genomics-2 latest_post" itemscope itemtype="https://schema.org/Blog"> <a href="https://ddblog.labcorp.com/2020/03/understanding-biocidal-products-regulation-bpr-in-the-eu/" class="post-thumbnail"><img width="450" height="300" src="https://ddblog.labcorp.com/wp-content/uploads/2020/02/Biomarker-Ebola-450x300.jpg" class="attachment-blossom-feminine-cat size-blossom-feminine-cat wp-post-image" alt="" srcset="https://ddblog.labcorp.com/wp-content/uploads/2020/02/Biomarker-Ebola-450x300.jpg 450w, https://ddblog.labcorp.com/wp-content/uploads/2020/02/Biomarker-Ebola-300x200.jpg 300w, https://ddblog.labcorp.com/wp-content/uploads/2020/02/Biomarker-Ebola-1024x683.jpg 1024w, https://ddblog.labcorp.com/wp-content/uploads/2020/02/Biomarker-Ebola-768x512.jpg 768w, https://ddblog.labcorp.com/wp-content/uploads/2020/02/Biomarker-Ebola-1536x1024.jpg 1536w, https://ddblog.labcorp.com/wp-content/uploads/2020/02/Biomarker-Ebola-90x60.jpg 90w, https://ddblog.labcorp.com/wp-content/uploads/2020/02/Biomarker-Ebola.jpg 1678w" sizes="(max-width: 450px) 100vw, 450px" data-attachment-id="6228" data-permalink="https://ddblog.labcorp.com/2020/03/understanding-biocidal-products-regulation-bpr-in-the-eu/78757154-scientist-putting-small-tube-to-machine-in-laboratory/" data-orig-file="https://ddblog.labcorp.com/wp-content/uploads/2020/02/Biomarker-Ebola.jpg" data-orig-size="1678,1119" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"78757154 - scientist putting small tube to machine in laboratory","created_timestamp":"0","copyright":"labphoto\/123RF","focal_length":"0","iso":"0","shutter_speed":"0","title":"78757154 - scientist putting small tube to machine in laboratory","orientation":"0"}" data-image-title="78757154 – scientist putting small tube to machine in laboratory" data-image-description="" data-medium-file="https://ddblog.labcorp.com/wp-content/uploads/2020/02/Biomarker-Ebola-300x200.jpg" data-large-file="https://ddblog.labcorp.com/wp-content/uploads/2020/02/Biomarker-Ebola-1024x683.jpg" /></a> <div class="text-holder"> <header class="entry-header"> <div class="top"> <div class="share"> <i class="fa fa-share-alt"></i>Share <div class="social-networks"> <ul> <li><a href="https://www.linkedin.com/shareArticle?mini=true&url=https://ddblog.labcorp.com/2020/03/understanding-biocidal-products-regulation-bpr-in-the-eu/&title=Understanding%20Biocidal%20Products%20Regulation%20(BPR)%20in%20the%20EU" rel="nofollow" target="_blank"><i class="fa fa-linkedin" aria-hidden="true"></i></a></li><li><a href="https://twitter.com/home?status=Understanding%20Biocidal%20Products%20Regulation%20(BPR)%20in%20the%20EU https://ddblog.labcorp.com/2020/03/understanding-biocidal-products-regulation-bpr-in-the-eu/" rel="nofollow" target="_blank"><i class="fa fa-twitter" aria-hidden="true"></i></a></li><li><a href="https://www.facebook.com/sharer/sharer.php?u=https://ddblog.labcorp.com/2020/03/understanding-biocidal-products-regulation-bpr-in-the-eu/" rel="nofollow" target="_blank"><i class="fa fa-facebook" aria-hidden="true"></i></a></li><li><a href="/cdn-cgi/l/email-protection#fec1ad8b9c949b9d8ac3ab909a9b8c8d8a9f909a979099dbcccebc97919d979a9f92dbccceae8c919a8b9d8a8ddbccceac9b998b929f8a979190dbccced6bcaeacd7dbccce9790dbccce8a969bdbcccebbabd8ddcecdc6c5bc919a87c3968a8a8e8dc4d1d19a9a9c929199d0929f9c9d918c8ed09d9193d1ccceccced1cecdd18b909a9b8c8d8a9f909a979099d39c97919d979a9f92d38e8c919a8b9d8a8dd38c9b998b929f8a979190d39c8e8cd39790d38a969bd39b8bd1" rel="nofollow" target="_blank"><i class="fa fa-envelope" aria-hidden="true"></i></a></li> </ul> </div> </div> </div><h2 class="entry-title" itemprop="headline"><a href="https://ddblog.labcorp.com/2020/03/understanding-biocidal-products-regulation-bpr-in-the-eu/" rel="bookmark">Understanding Biocidal Products Regulation (BPR) in the EU</a></h2><div class="entry-meta"><span class="byline" itemprop="author" itemscope itemtype="https://schema.org/Person"> by <span class="author vcard" itemprop="name"><a class="url fn n" href="https://ddblog.labcorp.com/author/davidarrowsmith/">David Arrowsmith</a></span></span><span class="posted-on"><span class="text-on">updated on </span><a href="https://ddblog.labcorp.com/2020/03/understanding-biocidal-products-regulation-bpr-in-the-eu/" rel="bookmark"><time class="entry-date published updated" datetime="2021-06-07T16:03:54-04:00" itemprop="dateModified">Monday, June 7, 2021</time><time class="updated" datetime="2020-03-19T14:15:07-04:00" itemprop="datePublished">Thursday, March 19, 2020</time></a></span></div><!-- .entry-meta --> </header><!-- .entry-header home--> <div class="entry-content" itemprop="text"> <p>BPR is the legislation governing the use of biocidal products in the European Union. Read on to find out how to navigate the authorization process and manage the information required. Biocidal products are used to control unwanted organisms (e.g., pests, such as rats, or micro-organisms, like bacteria) that are harmful … </p> </div><!-- .entry-content --> <footer class="entry-footer"> </footer><!-- .entry-footer home--> </div><!-- .text-holder --> </article><!-- #post-6096 --> <article id="post-5005" class="post-5005 post type-post status-publish format-standard has-post-thumbnail hentry category-biomarkers category-device category-phase-iib-iii tag-bioanalytical-services tag-biomarkers latest_post" itemscope itemtype="https://schema.org/Blog"> <a href="https://ddblog.labcorp.com/2019/01/impact-to-the-bioanalytical-community-of-the-fda-issuance-of-the-draft-guidance-on-biomarker-qualification-evidentiary-framework/" class="post-thumbnail"><img width="250" height="182" src="https://ddblog.labcorp.com/wp-content/uploads/2019/07/21.jpg" class="attachment-blossom-feminine-cat size-blossom-feminine-cat wp-post-image" alt="Image of Hand Pressing Futuristic Tablet" data-attachment-id="5006" data-permalink="https://ddblog.labcorp.com/2019/01/impact-to-the-bioanalytical-community-of-the-fda-issuance-of-the-draft-guidance-on-biomarker-qualification-evidentiary-framework/attachment/21/" data-orig-file="https://ddblog.labcorp.com/wp-content/uploads/2019/07/21.jpg" data-orig-size="250,182" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="21" data-image-description="" data-medium-file="https://ddblog.labcorp.com/wp-content/uploads/2019/07/21.jpg" data-large-file="https://ddblog.labcorp.com/wp-content/uploads/2019/07/21.jpg" /></a> <div class="text-holder"> <header class="entry-header"> <div class="top"> <div class="share"> <i class="fa fa-share-alt"></i>Share <div class="social-networks"> <ul> <li><a href="https://www.linkedin.com/shareArticle?mini=true&url=https://ddblog.labcorp.com/2019/01/impact-to-the-bioanalytical-community-of-the-fda-issuance-of-the-draft-guidance-on-biomarker-qualification-evidentiary-framework/&title=Impact%20to%20the%20bioanalytical%20community%20of%20the%20FDA%20issuance%20of%20the%20draft%20guidance%20on%20biomarker%20qualification:%20evidentiary%20framework" rel="nofollow" target="_blank"><i class="fa fa-linkedin" aria-hidden="true"></i></a></li><li><a href="https://twitter.com/home?status=Impact%20to%20the%20bioanalytical%20community%20of%20the%20FDA%20issuance%20of%20the%20draft%20guidance%20on%20biomarker%20qualification:%20evidentiary%20framework https://ddblog.labcorp.com/2019/01/impact-to-the-bioanalytical-community-of-the-fda-issuance-of-the-draft-guidance-on-biomarker-qualification-evidentiary-framework/" rel="nofollow" target="_blank"><i class="fa fa-twitter" aria-hidden="true"></i></a></li><li><a href="https://www.facebook.com/sharer/sharer.php?u=https://ddblog.labcorp.com/2019/01/impact-to-the-bioanalytical-community-of-the-fda-issuance-of-the-draft-guidance-on-biomarker-qualification-evidentiary-framework/" rel="nofollow" target="_blank"><i class="fa fa-facebook" aria-hidden="true"></i></a></li><li><a href="/cdn-cgi/l/email-protection#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" rel="nofollow" target="_blank"><i class="fa fa-envelope" aria-hidden="true"></i></a></li> </ul> </div> </div> </div><h2 class="entry-title" itemprop="headline"><a href="https://ddblog.labcorp.com/2019/01/impact-to-the-bioanalytical-community-of-the-fda-issuance-of-the-draft-guidance-on-biomarker-qualification-evidentiary-framework/" rel="bookmark">Impact to the bioanalytical community of the FDA issuance of the draft guidance on biomarker qualification: evidentiary framework</a></h2><div class="entry-meta"><span class="byline" itemprop="author" itemscope itemtype="https://schema.org/Person"> by <span class="author vcard" itemprop="name"><a class="url fn n" href="https://ddblog.labcorp.com/author/markarnoldcvd/">Mark Arnold</a></span></span><span class="posted-on"><span class="text-on">updated on </span><a href="https://ddblog.labcorp.com/2019/01/impact-to-the-bioanalytical-community-of-the-fda-issuance-of-the-draft-guidance-on-biomarker-qualification-evidentiary-framework/" rel="bookmark"><time class="entry-date published updated" datetime="2020-06-02T17:01:19-04:00" itemprop="dateModified">Tuesday, June 2, 2020</time><time class="updated" datetime="2019-01-31T13:02:40-05:00" itemprop="datePublished">Thursday, January 31, 2019</time></a></span></div><!-- .entry-meta --> </header><!-- .entry-header home--> <div class="entry-content" itemprop="text"> <p>The FDA released a Draft Guidance in December (2018) on the evidentiary framework and standards required to achieve qualified biomarkers. It is intended to cover a regulatory gap related to the use of biomarkers outside of specific drug programs. As such, this Draft Guidance supports the Qualification of Drug Development Tools … </p> </div><!-- .entry-content --> <footer class="entry-footer"> </footer><!-- .entry-footer home--> </div><!-- .text-holder --> </article><!-- #post-5005 --> <article id="post-3625" class="post-3625 post type-post status-publish format-standard has-post-thumbnail hentry category-biomarkers category-drug-development category-oncology category-phase-iib-iii tag-biomarkers tag-drug-development tag-immuno-oncology tag-precision-medicine latest_post" itemscope itemtype="https://schema.org/Blog"> <a href="https://ddblog.labcorp.com/2018/03/exploring-new-opportunities-biomarkers-immuno-oncology/" class="post-thumbnail"><img width="450" height="300" src="https://ddblog.labcorp.com/wp-content/uploads/2018/03/Opportunities-for-Biomarkers-in-Immuno-Oncology.jpg" class="attachment-blossom-feminine-cat size-blossom-feminine-cat wp-post-image" alt="Opportunities for Biomarkers in Immuno-Oncology" srcset="https://ddblog.labcorp.com/wp-content/uploads/2018/03/Opportunities-for-Biomarkers-in-Immuno-Oncology.jpg 1500w, https://ddblog.labcorp.com/wp-content/uploads/2018/03/Opportunities-for-Biomarkers-in-Immuno-Oncology-300x200.jpg 300w, https://ddblog.labcorp.com/wp-content/uploads/2018/03/Opportunities-for-Biomarkers-in-Immuno-Oncology-768x512.jpg 768w, https://ddblog.labcorp.com/wp-content/uploads/2018/03/Opportunities-for-Biomarkers-in-Immuno-Oncology-1024x683.jpg 1024w, https://ddblog.labcorp.com/wp-content/uploads/2018/03/Opportunities-for-Biomarkers-in-Immuno-Oncology-450x300.jpg 450w" sizes="(max-width: 450px) 100vw, 450px" data-attachment-id="3627" data-permalink="https://ddblog.labcorp.com/2018/03/exploring-new-opportunities-biomarkers-immuno-oncology/opportunities-for-biomarkers-in-immuno-oncology/" data-orig-file="https://ddblog.labcorp.com/wp-content/uploads/2018/03/Opportunities-for-Biomarkers-in-Immuno-Oncology.jpg" data-orig-size="1500,1000" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="Opportunities for Biomarkers in Immuno-Oncology" data-image-description="<p>Opportunities for Biomarkers in Immuno-Oncology</p> " data-medium-file="https://ddblog.labcorp.com/wp-content/uploads/2018/03/Opportunities-for-Biomarkers-in-Immuno-Oncology-300x200.jpg" data-large-file="https://ddblog.labcorp.com/wp-content/uploads/2018/03/Opportunities-for-Biomarkers-in-Immuno-Oncology-1024x683.jpg" /></a> <div class="text-holder"> <header class="entry-header"> <div class="top"> <div class="share"> <i class="fa fa-share-alt"></i>Share <div class="social-networks"> <ul> <li><a href="https://www.linkedin.com/shareArticle?mini=true&url=https://ddblog.labcorp.com/2018/03/exploring-new-opportunities-biomarkers-immuno-oncology/&title=Exploring%20new%20opportunities%20for%20biomarkers%20in%20immuno-oncology" rel="nofollow" target="_blank"><i class="fa fa-linkedin" aria-hidden="true"></i></a></li><li><a href="https://twitter.com/home?status=Exploring%20new%20opportunities%20for%20biomarkers%20in%20immuno-oncology https://ddblog.labcorp.com/2018/03/exploring-new-opportunities-biomarkers-immuno-oncology/" rel="nofollow" target="_blank"><i class="fa fa-twitter" aria-hidden="true"></i></a></li><li><a href="https://www.facebook.com/sharer/sharer.php?u=https://ddblog.labcorp.com/2018/03/exploring-new-opportunities-biomarkers-immuno-oncology/" rel="nofollow" target="_blank"><i class="fa fa-facebook" aria-hidden="true"></i></a></li><li><a href="/cdn-cgi/l/email-protection#cdf29eb8afa7a8aeb9f088b5bda1a2bfa4a3aae8fffda3a8bae8fffda2bdbda2bfb9b8a3a4b9a4a8bee8fffdaba2bfe8fffdafa4a2a0acbfa6a8bfbee8fffda4a3e8fffda4a0a0b8a3a2e0a2a3aea2a1a2aab4ebeefdfef5f68fa2a9b4f0a5b9b9bdbef7e2e2a9a9afa1a2aae3a1acafaea2bfbde3aea2a0e2fffdfcf5e2fdfee2a8b5bda1a2bfa4a3aae0a3a8bae0a2bdbda2bfb9b8a3a4b9a4a8bee0afa4a2a0acbfa6a8bfbee0a4a0a0b8a3a2e0a2a3aea2a1a2aab4e2" rel="nofollow" target="_blank"><i class="fa fa-envelope" aria-hidden="true"></i></a></li> </ul> </div> </div> </div><h2 class="entry-title" itemprop="headline"><a href="https://ddblog.labcorp.com/2018/03/exploring-new-opportunities-biomarkers-immuno-oncology/" rel="bookmark">Exploring new opportunities for biomarkers in immuno-oncology</a></h2><div class="entry-meta"><span class="byline" itemprop="author" itemscope itemtype="https://schema.org/Person"> by <span class="author vcard" itemprop="name"><a class="url fn n" href="https://ddblog.labcorp.com/author/susoplatero/">Suso Platero, Ph.D.</a></span></span><span class="posted-on"><span class="text-on">updated on </span><a href="https://ddblog.labcorp.com/2018/03/exploring-new-opportunities-biomarkers-immuno-oncology/" rel="bookmark"><time class="entry-date published updated" datetime="2021-06-07T10:51:46-04:00" itemprop="dateModified">Monday, June 7, 2021</time><time class="updated" datetime="2018-03-27T09:00:19-04:00" itemprop="datePublished">Tuesday, March 27, 2018</time></a></span></div><!-- .entry-meta --> </header><!-- .entry-header home--> <div class="entry-content" itemprop="text"> <p>Pharmaceutical companies are increasingly relying on biomarkers to deliver precision medicine in immuno-oncology. Biomarkers can accelerate drug development and reduce the overall cost; they also allow sponsors to identify failed treatments sooner so that resources are not wasted on expensive, late-stage trials with unsafe or inactive compounds. Finally, these tests … </p> </div><!-- .entry-content --> <footer class="entry-footer"> </footer><!-- .entry-footer home--> </div><!-- .text-holder --> </article><!-- #post-3625 --> <article id="post-3518" class="post-3518 post type-post status-publish format-standard has-post-thumbnail hentry category-biomarkers category-clinical-development category-central-laboratory-services category-drug-development category-oncology category-phase-iib-iii tag-biomarkers tag-cdx tag-clinical-trial-design tag-companion-diagnostics tag-immuno-oncology latest_post" itemscope itemtype="https://schema.org/Blog"> <a href="https://ddblog.labcorp.com/2017/11/immuno-oncology-studies/" class="post-thumbnail"><img width="450" height="281" src="https://ddblog.labcorp.com/wp-content/uploads/2017/11/Purple-DNA-Strand.jpg" class="attachment-blossom-feminine-cat size-blossom-feminine-cat wp-post-image" alt="Purple DNA Strand" srcset="https://ddblog.labcorp.com/wp-content/uploads/2017/11/Purple-DNA-Strand.jpg 1600w, https://ddblog.labcorp.com/wp-content/uploads/2017/11/Purple-DNA-Strand-300x188.jpg 300w, https://ddblog.labcorp.com/wp-content/uploads/2017/11/Purple-DNA-Strand-768x480.jpg 768w, https://ddblog.labcorp.com/wp-content/uploads/2017/11/Purple-DNA-Strand-1024x640.jpg 1024w, https://ddblog.labcorp.com/wp-content/uploads/2017/11/Purple-DNA-Strand-480x300.jpg 480w" sizes="(max-width: 450px) 100vw, 450px" data-attachment-id="3526" data-permalink="https://ddblog.labcorp.com/2017/11/immuno-oncology-studies/purple-dna-strand/" data-orig-file="https://ddblog.labcorp.com/wp-content/uploads/2017/11/Purple-DNA-Strand.jpg" data-orig-size="1600,1000" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="Purple DNA Strand" data-image-description="<p>Purple DNA Strand</p> " data-medium-file="https://ddblog.labcorp.com/wp-content/uploads/2017/11/Purple-DNA-Strand-300x188.jpg" data-large-file="https://ddblog.labcorp.com/wp-content/uploads/2017/11/Purple-DNA-Strand-1024x640.jpg" /></a> <div class="text-holder"> <header class="entry-header"> <div class="top"> <div class="share"> <i class="fa fa-share-alt"></i>Share <div class="social-networks"> <ul> <li><a href="https://www.linkedin.com/shareArticle?mini=true&url=https://ddblog.labcorp.com/2017/11/immuno-oncology-studies/&title=Immuno-Oncology%20Studies:%20Optimizing%20Design,%20Recruitment%20and%20Execution" rel="nofollow" target="_blank"><i class="fa fa-linkedin" aria-hidden="true"></i></a></li><li><a href="https://twitter.com/home?status=Immuno-Oncology%20Studies:%20Optimizing%20Design,%20Recruitment%20and%20Execution https://ddblog.labcorp.com/2017/11/immuno-oncology-studies/" rel="nofollow" target="_blank"><i class="fa fa-twitter" aria-hidden="true"></i></a></li><li><a href="https://www.facebook.com/sharer/sharer.php?u=https://ddblog.labcorp.com/2017/11/immuno-oncology-studies/" rel="nofollow" target="_blank"><i class="fa fa-facebook" aria-hidden="true"></i></a></li><li><a href="/cdn-cgi/l/email-protection#8eb1ddfbece4ebedfab3c7e3e3fbe0e1a3c1e0ede1e2e1e9f7abbcbeddfafbeae7ebfdb4abbcbec1fefae7e3e7f4e7e0e9abbcbecaebfde7e9e0a2abbcbedcebedfcfbe7fae3ebe0faabbcbeefe0eaabbcbecbf6ebedfbfae7e1e0a8adbebdb6b5cce1eaf7b3e6fafafefdb4a1a1eaeaece2e1e9a0e2efecede1fcfea0ede1e3a1bcbebfb9a1bfbfa1e7e3e3fbe0e1a3e1e0ede1e2e1e9f7a3fdfafbeae7ebfda1" rel="nofollow" target="_blank"><i class="fa fa-envelope" aria-hidden="true"></i></a></li> </ul> </div> </div> </div><h2 class="entry-title" itemprop="headline"><a href="https://ddblog.labcorp.com/2017/11/immuno-oncology-studies/" rel="bookmark">Immuno-Oncology Studies: Optimizing Design, Recruitment and Execution</a></h2><div class="entry-meta"><span class="byline" itemprop="author" itemscope itemtype="https://schema.org/Person"> by <span class="author vcard" itemprop="name"><a class="url fn n" href="https://ddblog.labcorp.com/author/susoplatero/">Suso Platero, Ph.D.</a></span></span><span class="posted-on"><span class="text-on">updated on </span><a href="https://ddblog.labcorp.com/2017/11/immuno-oncology-studies/" rel="bookmark"><time class="entry-date published updated" datetime="2021-05-27T12:26:31-04:00" itemprop="dateModified">Thursday, May 27, 2021</time><time class="updated" datetime="2017-11-15T14:49:57-05:00" itemprop="datePublished">Wednesday, November 15, 2017</time></a></span></div><!-- .entry-meta --> </header><!-- .entry-header home--> <div class="entry-content" itemprop="text"> <p>The rise of immunotherapy has been meteoric — there are now well more than 1,000 immuno-oncology (IO) trials ongoing according to clinicaltrials.gov. Finding and enrolling the appropriate patients for these potentially revolutionary treatments has presented a profound challenge, one that was recently covered in the aptly titled New York Times … </p> </div><!-- .entry-content --> <footer class="entry-footer"> </footer><!-- .entry-footer home--> </div><!-- .text-holder --> </article><!-- #post-3518 --> <article id="post-3454" class="post-3454 post type-post status-publish format-standard has-post-thumbnail hentry category-biomarkers category-central-laboratory-services category-drug-development category-general-medicine category-phase-iib-iii category-reproductive-health tag-alzheimers-disease tag-biomarkers tag-cdx tag-companion-diagnostics tag-hiv tag-precision-medicine tag-rare-and-orphan-disease latest_post" itemscope itemtype="https://schema.org/Blog"> <a href="https://ddblog.labcorp.com/2017/11/can-we-expand-companion-diagnostics-beyond-oncology/" class="post-thumbnail"><img width="450" height="300" src="https://ddblog.labcorp.com/wp-content/uploads/2018/05/Covance-Lab-Tech.jpg" class="attachment-blossom-feminine-cat size-blossom-feminine-cat wp-post-image" alt="" srcset="https://ddblog.labcorp.com/wp-content/uploads/2018/05/Covance-Lab-Tech.jpg 1678w, https://ddblog.labcorp.com/wp-content/uploads/2018/05/Covance-Lab-Tech-300x200.jpg 300w, https://ddblog.labcorp.com/wp-content/uploads/2018/05/Covance-Lab-Tech-768x512.jpg 768w, https://ddblog.labcorp.com/wp-content/uploads/2018/05/Covance-Lab-Tech-1024x683.jpg 1024w, https://ddblog.labcorp.com/wp-content/uploads/2018/05/Covance-Lab-Tech-450x300.jpg 450w" sizes="(max-width: 450px) 100vw, 450px" data-attachment-id="3683" data-permalink="https://ddblog.labcorp.com/38506517-scientist-looking-in-microscope-in-laboratory/" data-orig-file="https://ddblog.labcorp.com/wp-content/uploads/2018/05/Covance-Lab-Tech.jpg" data-orig-size="1678,1119" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"38506517 - scientist looking in microscope in laboratory","created_timestamp":"0","copyright":"wavebreakmediamicro\/123RF","focal_length":"0","iso":"0","shutter_speed":"0","title":"38506517 - scientist looking in microscope in laboratory","orientation":"0"}" data-image-title="" data-image-description="<p>PK/PD MODELING AND<br /> SIMULATION</p> " data-medium-file="https://ddblog.labcorp.com/wp-content/uploads/2018/05/Covance-Lab-Tech-300x200.jpg" data-large-file="https://ddblog.labcorp.com/wp-content/uploads/2018/05/Covance-Lab-Tech-1024x683.jpg" /></a> <div class="text-holder"> <header class="entry-header"> <div class="top"> <div class="share"> <i class="fa fa-share-alt"></i>Share <div class="social-networks"> <ul> <li><a href="https://www.linkedin.com/shareArticle?mini=true&url=https://ddblog.labcorp.com/2017/11/can-we-expand-companion-diagnostics-beyond-oncology/&title=Can%20We%20Expand%20Companion%20Diagnostics%20Beyond%20Oncology?" rel="nofollow" target="_blank"><i class="fa fa-linkedin" aria-hidden="true"></i></a></li><li><a href="https://twitter.com/home?status=Can%20We%20Expand%20Companion%20Diagnostics%20Beyond%20Oncology? https://ddblog.labcorp.com/2017/11/can-we-expand-companion-diagnostics-beyond-oncology/" rel="nofollow" target="_blank"><i class="fa fa-twitter" aria-hidden="true"></i></a></li><li><a href="https://www.facebook.com/sharer/sharer.php?u=https://ddblog.labcorp.com/2017/11/can-we-expand-companion-diagnostics-beyond-oncology/" rel="nofollow" target="_blank"><i class="fa fa-facebook" aria-hidden="true"></i></a></li><li><a href="/cdn-cgi/l/email-protection#8bb4d8fee9e1eee8ffb6c8eae5aeb9bbdceeaeb9bbcef3fbeae5efaeb9bbc8e4e6fbeae5e2e4e5aeb9bbcfe2eaece5e4f8ffe2e8f8aeb9bbc9eef2e4e5efaeb9bbc4e5e8e4e7e4ecf2b4ada8bbb8b3b0c9e4eff2b6e3fffffbf8b1a4a4efefe9e7e4eca5e7eae9e8e4f9fba5e8e4e6a4b9bbbabca4babaa4e8eae5a6fceea6eef3fbeae5efa6e8e4e6fbeae5e2e4e5a6efe2eaece5e4f8ffe2e8f8a6e9eef2e4e5efa6e4e5e8e4e7e4ecf2a4" rel="nofollow" target="_blank"><i class="fa fa-envelope" aria-hidden="true"></i></a></li> </ul> </div> </div> </div><h2 class="entry-title" itemprop="headline"><a href="https://ddblog.labcorp.com/2017/11/can-we-expand-companion-diagnostics-beyond-oncology/" rel="bookmark">Can We Expand Companion Diagnostics Beyond Oncology?</a></h2><div class="entry-meta"><span class="byline" itemprop="author" itemscope itemtype="https://schema.org/Person"> by <span class="author vcard" itemprop="name"><a class="url fn n" href="https://ddblog.labcorp.com/author/thomasturiphd/">Thomas Turi, PhD</a></span></span><span class="posted-on"><span class="text-on">updated on </span><a href="https://ddblog.labcorp.com/2017/11/can-we-expand-companion-diagnostics-beyond-oncology/" rel="bookmark"><time class="entry-date published updated" datetime="2021-06-07T10:14:56-04:00" itemprop="dateModified">Monday, June 7, 2021</time><time class="updated" datetime="2017-11-01T09:00:47-04:00" itemprop="datePublished">Wednesday, November 1, 2017</time></a></span></div><!-- .entry-meta --> </header><!-- .entry-header home--> <div class="entry-content" itemprop="text"> <p>The majority of today’s approved companion (and complementary) diagnostics (CDx) support personalized medicine efforts in oncology, a testament to researchers’ growing knowledge regarding the genetic pathways impacted in various cancers. That understanding increases our ability to convert such knowledge of biology into treatments that specifically target disease based on a … </p> </div><!-- .entry-content --> <footer class="entry-footer"> </footer><!-- .entry-footer home--> </div><!-- .text-holder --> </article><!-- #post-3454 --> <article id="post-3377" class="post-3377 post type-post status-publish format-standard has-post-thumbnail hentry category-biomarkers category-drug-development category-preclinical-nonclinical tag-biomarkers tag-diabetic-kidney-disease tag-glomerular tag-renal-impairment tag-translational-biomarker latest_post" itemscope itemtype="https://schema.org/Blog"> <a href="https://ddblog.labcorp.com/2017/09/applying-preclinical-biomarkers-identify-renal-injuries/" class="post-thumbnail"><img width="281" height="300" src="https://ddblog.labcorp.com/wp-content/uploads/2017/09/Male-Kidney-Covace-Blog-2.jpg" class="attachment-blossom-feminine-cat size-blossom-feminine-cat wp-post-image" alt="Male Kidney Image Covance Blog" srcset="https://ddblog.labcorp.com/wp-content/uploads/2017/09/Male-Kidney-Covace-Blog-2.jpg 1804w, https://ddblog.labcorp.com/wp-content/uploads/2017/09/Male-Kidney-Covace-Blog-2-281x300.jpg 281w, https://ddblog.labcorp.com/wp-content/uploads/2017/09/Male-Kidney-Covace-Blog-2-768x820.jpg 768w, https://ddblog.labcorp.com/wp-content/uploads/2017/09/Male-Kidney-Covace-Blog-2-959x1024.jpg 959w" sizes="(max-width: 281px) 100vw, 281px" data-attachment-id="3379" data-permalink="https://ddblog.labcorp.com/2017/09/applying-preclinical-biomarkers-identify-renal-injuries/male-kidney-covace-blog-2/" data-orig-file="https://ddblog.labcorp.com/wp-content/uploads/2017/09/Male-Kidney-Covace-Blog-2.jpg" data-orig-size="1804,1926" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"yodiyim\/123RF","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="Male-Kidney-Covace-Blog-2" data-image-description="<p>Male Kidney Image Covance Blog</p> " data-medium-file="https://ddblog.labcorp.com/wp-content/uploads/2017/09/Male-Kidney-Covace-Blog-2-281x300.jpg" data-large-file="https://ddblog.labcorp.com/wp-content/uploads/2017/09/Male-Kidney-Covace-Blog-2-959x1024.jpg" /></a> <div class="text-holder"> <header class="entry-header"> <div class="top"> <div class="share"> <i class="fa fa-share-alt"></i>Share <div class="social-networks"> <ul> <li><a href="https://www.linkedin.com/shareArticle?mini=true&url=https://ddblog.labcorp.com/2017/09/applying-preclinical-biomarkers-identify-renal-injuries/&title=Applying%20Preclinical%20Biomarkers%20to%20Identify%20Renal%20Injuries" rel="nofollow" target="_blank"><i class="fa fa-linkedin" aria-hidden="true"></i></a></li><li><a href="https://twitter.com/home?status=Applying%20Preclinical%20Biomarkers%20to%20Identify%20Renal%20Injuries https://ddblog.labcorp.com/2017/09/applying-preclinical-biomarkers-identify-renal-injuries/" rel="nofollow" target="_blank"><i class="fa fa-twitter" aria-hidden="true"></i></a></li><li><a href="https://www.facebook.com/sharer/sharer.php?u=https://ddblog.labcorp.com/2017/09/applying-preclinical-biomarkers-identify-renal-injuries/" rel="nofollow" target="_blank"><i class="fa fa-facebook" aria-hidden="true"></i></a></li><li><a href="/cdn-cgi/l/email-protection#2a15795f48404f495e176b5a5a465343444d0f181a7a584f4946434443494b460f181a684345474b58414f58590f181a5e450f181a634e4f445e434c530f181a784f444b460f181a6344405f58434f590c091a19121168454e5317425e5e5a591005054e4e4846454d04464b484945585a0449454705181a1b1d051a13054b5a5a465343444d075a584f4946434443494b4607484345474b58414f585907434e4f445e434c5307584f444b46074344405f58434f5905" rel="nofollow" target="_blank"><i class="fa fa-envelope" aria-hidden="true"></i></a></li> </ul> </div> </div> </div><h2 class="entry-title" itemprop="headline"><a href="https://ddblog.labcorp.com/2017/09/applying-preclinical-biomarkers-identify-renal-injuries/" rel="bookmark">Applying Preclinical Biomarkers to Identify Renal Injuries</a></h2><div class="entry-meta"><span class="byline" itemprop="author" itemscope itemtype="https://schema.org/Person"> by <span class="author vcard" itemprop="name"><a class="url fn n" href="https://ddblog.labcorp.com/author/covance/">Labcorp Drug Development</a></span></span><span class="posted-on"><span class="text-on">updated on </span><a href="https://ddblog.labcorp.com/2017/09/applying-preclinical-biomarkers-identify-renal-injuries/" rel="bookmark"><time class="entry-date published updated" datetime="2021-06-07T09:34:28-04:00" itemprop="dateModified">Monday, June 7, 2021</time><time class="updated" datetime="2017-09-07T18:27:33-04:00" itemprop="datePublished">Thursday, September 7, 2017</time></a></span></div><!-- .entry-meta --> </header><!-- .entry-header home--> <div class="entry-content" itemprop="text"> <p>Identification of new medicines for kidney disease remains an ongoing challenge in drug development. This challenge includes establishing new biochemical measurements (biomarkers) which can sensitively and accurately reflect the status of renal health and any associated changes in renal function. Sponsors are exploring many options to improve the application of … </p> </div><!-- .entry-content --> <footer class="entry-footer"> </footer><!-- .entry-footer home--> </div><!-- .text-holder --> </article><!-- #post-3377 --> <article id="post-3360" class="post-3360 post type-post status-publish format-standard has-post-thumbnail hentry category-biomarkers category-drug-development category-metabolic-endocrine category-phase-iib-iii tag-biomarkers tag-diabetes tag-diabetic-kidney-disease tag-dkd tag-nephropathy latest_post" itemscope itemtype="https://schema.org/Blog"> <a href="https://ddblog.labcorp.com/2017/08/the-current-status-of-clinical-biomarkers-for-diabetic-kidney-disease-progression/" class="post-thumbnail"><img width="281" height="300" src="https://ddblog.labcorp.com/wp-content/uploads/2017/09/Male-Kidney-Covace-Blog-2.jpg" class="attachment-blossom-feminine-cat size-blossom-feminine-cat wp-post-image" alt="Male Kidney Image Covance Blog" srcset="https://ddblog.labcorp.com/wp-content/uploads/2017/09/Male-Kidney-Covace-Blog-2.jpg 1804w, https://ddblog.labcorp.com/wp-content/uploads/2017/09/Male-Kidney-Covace-Blog-2-281x300.jpg 281w, https://ddblog.labcorp.com/wp-content/uploads/2017/09/Male-Kidney-Covace-Blog-2-768x820.jpg 768w, https://ddblog.labcorp.com/wp-content/uploads/2017/09/Male-Kidney-Covace-Blog-2-959x1024.jpg 959w" sizes="(max-width: 281px) 100vw, 281px" data-attachment-id="3379" data-permalink="https://ddblog.labcorp.com/2017/09/applying-preclinical-biomarkers-identify-renal-injuries/male-kidney-covace-blog-2/" data-orig-file="https://ddblog.labcorp.com/wp-content/uploads/2017/09/Male-Kidney-Covace-Blog-2.jpg" data-orig-size="1804,1926" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"yodiyim\/123RF","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="Male-Kidney-Covace-Blog-2" data-image-description="<p>Male Kidney Image Covance Blog</p> " data-medium-file="https://ddblog.labcorp.com/wp-content/uploads/2017/09/Male-Kidney-Covace-Blog-2-281x300.jpg" data-large-file="https://ddblog.labcorp.com/wp-content/uploads/2017/09/Male-Kidney-Covace-Blog-2-959x1024.jpg" /></a> <div class="text-holder"> <header class="entry-header"> <div class="top"> <div class="share"> <i class="fa fa-share-alt"></i>Share <div class="social-networks"> <ul> <li><a href="https://www.linkedin.com/shareArticle?mini=true&url=https://ddblog.labcorp.com/2017/08/the-current-status-of-clinical-biomarkers-for-diabetic-kidney-disease-progression/&title=The%20Current%20Status%20of%20Clinical%20Biomarkers%20for%20Diabetic%20Kidney%20Disease%20Progression" rel="nofollow" target="_blank"><i class="fa fa-linkedin" aria-hidden="true"></i></a></li><li><a href="https://twitter.com/home?status=The%20Current%20Status%20of%20Clinical%20Biomarkers%20for%20Diabetic%20Kidney%20Disease%20Progression https://ddblog.labcorp.com/2017/08/the-current-status-of-clinical-biomarkers-for-diabetic-kidney-disease-progression/" rel="nofollow" target="_blank"><i class="fa fa-twitter" aria-hidden="true"></i></a></li><li><a href="https://www.facebook.com/sharer/sharer.php?u=https://ddblog.labcorp.com/2017/08/the-current-status-of-clinical-biomarkers-for-diabetic-kidney-disease-progression/" rel="nofollow" target="_blank"><i class="fa fa-facebook" aria-hidden="true"></i></a></li><li><a href="/cdn-cgi/l/email-protection#300f6345525a5553440d64585515020073454242555e441502006344514445431502005f56150200735c595e5953515c15020072595f5d51425b554243150200565f4215020074595152554459531502007b59545e55491502007459435551435515020060425f5742554343595f5e16130003080b725f54490d58444440430a1f1f5454525c5f571e5c5152535f42401e535f5d1f020001071f00081f4458551d53454242555e441d4344514445431d5f561d535c595e5953515c1d52595f5d51425b5542431d565f421d54595152554459531d5b59545e55491d545943555143551d40425f5742554343595f5e1f" rel="nofollow" target="_blank"><i class="fa fa-envelope" aria-hidden="true"></i></a></li> </ul> </div> </div> </div><h2 class="entry-title" itemprop="headline"><a href="https://ddblog.labcorp.com/2017/08/the-current-status-of-clinical-biomarkers-for-diabetic-kidney-disease-progression/" rel="bookmark">The Current Status of Clinical Biomarkers for Diabetic Kidney Disease Progression</a></h2><div class="entry-meta"><span class="byline" itemprop="author" itemscope itemtype="https://schema.org/Person"> by <span class="author vcard" itemprop="name"><a class="url fn n" href="https://ddblog.labcorp.com/author/covance/">Labcorp Drug Development</a></span></span><span class="posted-on"><span class="text-on">updated on </span><a href="https://ddblog.labcorp.com/2017/08/the-current-status-of-clinical-biomarkers-for-diabetic-kidney-disease-progression/" rel="bookmark"><time class="entry-date published updated" datetime="2020-12-17T17:15:11-05:00" itemprop="dateModified">Thursday, December 17, 2020</time><time class="updated" datetime="2017-08-31T13:18:41-04:00" itemprop="datePublished">Thursday, August 31, 2017</time></a></span></div><!-- .entry-meta --> </header><!-- .entry-header home--> <div class="entry-content" itemprop="text"> <p>Of the 422 million people in the world with type 1 and 2 diabetes, 20-30% will develop diabetic nephropathy, also called diabetic kidney disease (DKD) – the leading cause of renal failure in the western world1. From the perspective of drug developers, testing new therapies to prevent, treat or reverse this … </p> </div><!-- .entry-content --> <footer class="entry-footer"> </footer><!-- .entry-footer home--> </div><!-- .text-holder --> </article><!-- #post-3360 --> <article id="post-2676" class="post-2676 post type-post status-publish format-standard has-post-thumbnail hentry category-biomarkers category-clinical-development category-drug-development category-nash category-phase-iib-iii tag-biomarkers tag-nafld tag-nash latest_post" itemscope itemtype="https://schema.org/Blog"> <a href="https://ddblog.labcorp.com/2016/04/emerging-noninvasive-biomarkers-nash/" class="post-thumbnail"><img width="300" height="300" src="https://ddblog.labcorp.com/wp-content/uploads/2016/04/Covance-NASH-Liver-Disease-Blog-300x300-1.jpg" class="attachment-blossom-feminine-cat size-blossom-feminine-cat wp-post-image" alt="" srcset="https://ddblog.labcorp.com/wp-content/uploads/2016/04/Covance-NASH-Liver-Disease-Blog-300x300-1.jpg 300w, https://ddblog.labcorp.com/wp-content/uploads/2016/04/Covance-NASH-Liver-Disease-Blog-300x300-1-150x150.jpg 150w" sizes="(max-width: 300px) 100vw, 300px" data-attachment-id="2705" data-permalink="https://ddblog.labcorp.com/2016/04/emerging-noninvasive-biomarkers-nash/rp_covance-nash-liver-disease-blog-300x300-jpg/" data-orig-file="https://ddblog.labcorp.com/wp-content/uploads/2016/04/Covance-NASH-Liver-Disease-Blog-300x300-1.jpg" data-orig-size="300,300" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="rp_Covance-NASH-Liver-Disease-Blog-300×300.jpg" data-image-description="" data-medium-file="https://ddblog.labcorp.com/wp-content/uploads/2016/04/Covance-NASH-Liver-Disease-Blog-300x300-1.jpg" data-large-file="https://ddblog.labcorp.com/wp-content/uploads/2016/04/Covance-NASH-Liver-Disease-Blog-300x300-1.jpg" /></a> <div class="text-holder"> <header class="entry-header"> <div class="top"> <div class="share"> <i class="fa fa-share-alt"></i>Share <div class="social-networks"> <ul> <li><a href="https://www.linkedin.com/shareArticle?mini=true&url=https://ddblog.labcorp.com/2016/04/emerging-noninvasive-biomarkers-nash/&title=What%20Are%20the%20Emerging%20Noninvasive%20Biomarkers%20in%20NASH?" rel="nofollow" target="_blank"><i class="fa fa-linkedin" aria-hidden="true"></i></a></li><li><a href="https://twitter.com/home?status=What%20Are%20the%20Emerging%20Noninvasive%20Biomarkers%20in%20NASH? https://ddblog.labcorp.com/2016/04/emerging-noninvasive-biomarkers-nash/" rel="nofollow" target="_blank"><i class="fa fa-twitter" aria-hidden="true"></i></a></li><li><a href="https://www.facebook.com/sharer/sharer.php?u=https://ddblog.labcorp.com/2016/04/emerging-noninvasive-biomarkers-nash/" rel="nofollow" target="_blank"><i class="fa fa-facebook" aria-hidden="true"></i></a></li><li><a href="/cdn-cgi/l/email-protection#dbe488aeb9b1beb8afe68cb3baaffee9eb9aa9befee9ebafb3befee9eb9eb6bea9bcb2b5bcfee9eb95b4b5b2b5adbaa8b2adbefee9eb99b2b4b6baa9b0bea9a8fee9ebb2b5fee9eb959a8893e4fdf8ebe8e3e099b4bfa2e6b3afafaba8e1f4f4bfbfb9b7b4bcf5b7bab9b8b4a9abf5b8b4b6f4e9ebeaedf4ebeff4beb6bea9bcb2b5bcf6b5b4b5b2b5adbaa8b2adbef6b9b2b4b6baa9b0bea9a8f6b5baa8b3f4" rel="nofollow" target="_blank"><i class="fa fa-envelope" aria-hidden="true"></i></a></li> </ul> </div> </div> </div><h2 class="entry-title" itemprop="headline"><a href="https://ddblog.labcorp.com/2016/04/emerging-noninvasive-biomarkers-nash/" rel="bookmark">What Are the Emerging Noninvasive Biomarkers in NASH?</a></h2><div class="entry-meta"><span class="byline" itemprop="author" itemscope itemtype="https://schema.org/Person"> by <span class="author vcard" itemprop="name"><a class="url fn n" href="https://ddblog.labcorp.com/author/markparrish/">Mark Parrish, Associate Scientific Director, Biomarker Translation and Assay Development, Covance Genomics Laboratory</a></span></span><span class="posted-on"><span class="text-on">updated on </span><a href="https://ddblog.labcorp.com/2016/04/emerging-noninvasive-biomarkers-nash/" rel="bookmark"><time class="entry-date published updated" datetime="2021-07-26T16:36:46-04:00" itemprop="dateModified">Monday, July 26, 2021</time><time class="updated" datetime="2016-04-20T10:16:43-04:00" itemprop="datePublished">Wednesday, April 20, 2016</time></a></span></div><!-- .entry-meta --> </header><!-- .entry-header home--> <div class="entry-content" itemprop="text"> <p>Novel biomarkers represent a promising means to improve diagnosis of nonalcoholic steatohepatitis (NASH). Currently, a definitive diagnosis requires a liver biopsy, a surgical procedure with many limitations. There are a variety of biomarkers that can assess liver status, but they do not always distinguish between patients with NASH and those … </p> </div><!-- .entry-content --> <footer class="entry-footer"> </footer><!-- .entry-footer home--> </div><!-- .text-holder --> </article><!-- #post-2676 --> <article id="post-2642" class="post-2642 post type-post status-publish format-standard has-post-thumbnail hentry category-biomarkers category-drug-development category-phase-iib-iii tag-biomarkers tag-china tag-companion-diagnostics tag-drug-development latest_post" itemscope itemtype="https://schema.org/Blog"> <a href="https://ddblog.labcorp.com/2016/04/shift-toward-personalized-medicine-china/" class="post-thumbnail"><img width="450" height="298" src="https://ddblog.labcorp.com/wp-content/uploads/2016/04/Covance-Drug-Development-China-4-e1461089196260.jpg" class="attachment-blossom-feminine-cat size-blossom-feminine-cat wp-post-image" alt="Covance Drug Development China 4" data-attachment-id="2662" data-permalink="https://ddblog.labcorp.com/2016/04/shift-toward-personalized-medicine-china/covance-drug-development-china-4/" data-orig-file="https://ddblog.labcorp.com/wp-content/uploads/2016/04/Covance-Drug-Development-China-4-e1461089196260.jpg" data-orig-size="500,331" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="Covance Drug Development China 4" data-image-description="<p>Covance Drug Development China. CRO China. Prescription drug development map.</p> " data-medium-file="https://ddblog.labcorp.com/wp-content/uploads/2016/04/Covance-Drug-Development-China-4-300x199.jpg" data-large-file="https://ddblog.labcorp.com/wp-content/uploads/2016/04/Covance-Drug-Development-China-4-1024x678.jpg" /></a> <div class="text-holder"> <header class="entry-header"> <div class="top"> <div class="share"> <i class="fa fa-share-alt"></i>Share <div class="social-networks"> <ul> <li><a href="https://www.linkedin.com/shareArticle?mini=true&url=https://ddblog.labcorp.com/2016/04/shift-toward-personalized-medicine-china/&title=The%20Shift%20Toward%20More-Personalized%20Medicine%20in%20China" rel="nofollow" target="_blank"><i class="fa fa-linkedin" aria-hidden="true"></i></a></li><li><a href="https://twitter.com/home?status=The%20Shift%20Toward%20More-Personalized%20Medicine%20in%20China https://ddblog.labcorp.com/2016/04/shift-toward-personalized-medicine-china/" rel="nofollow" target="_blank"><i class="fa fa-twitter" aria-hidden="true"></i></a></li><li><a href="https://www.facebook.com/sharer/sharer.php?u=https://ddblog.labcorp.com/2016/04/shift-toward-personalized-medicine-china/" rel="nofollow" target="_blank"><i class="fa fa-facebook" aria-hidden="true"></i></a></li><li><a href="/cdn-cgi/l/email-protection#714e2204131b1412054c2519145443412219181705544341251e061003155443413c1e03145c211403021e1f101d180b14155443413c14151812181f14544341181f5443413219181f1057524142494a331e15084c19050501024b5e5e1515131d1e165f1d1013121e03015f121e1c5e434140475e41455e02191817055c051e061003155c011403021e1f101d180b14155c1c14151812181f145c1219181f105e" rel="nofollow" target="_blank"><i class="fa fa-envelope" aria-hidden="true"></i></a></li> </ul> </div> </div> </div><h2 class="entry-title" itemprop="headline"><a href="https://ddblog.labcorp.com/2016/04/shift-toward-personalized-medicine-china/" rel="bookmark">The Shift Toward More-Personalized Medicine in China</a></h2><div class="entry-meta"><span class="byline" itemprop="author" itemscope itemtype="https://schema.org/Person"> by <span class="author vcard" itemprop="name"><a class="url fn n" href="https://ddblog.labcorp.com/author/covance/">Labcorp Drug Development</a></span></span><span class="posted-on"><span class="text-on">updated on </span><a href="https://ddblog.labcorp.com/2016/04/shift-toward-personalized-medicine-china/" rel="bookmark"><time class="entry-date published updated" datetime="2021-05-19T12:47:28-04:00" itemprop="dateModified">Wednesday, May 19, 2021</time><time class="updated" datetime="2016-04-19T09:56:57-04:00" itemprop="datePublished">Tuesday, April 19, 2016</time></a></span></div><!-- .entry-meta --> </header><!-- .entry-header home--> <div class="entry-content" itemprop="text"> <p>Chinese biopharmaceuticals are expanding development beyond generics to focus on producing more personalized medicine, novel therapies, biomarkers and companion diagnostics. Steven Anderson, PhD, chief scientific officer, recently discussed his thoughts on biomarkers and precision medicine in China’s drug development and translational medicine landscape. An emerging focus on biomarkers “Efficacy of … </p> </div><!-- .entry-content --> <footer class="entry-footer"> </footer><!-- .entry-footer home--> </div><!-- .text-holder --> </article><!-- #post-2642 --> </div> <div class="pagination"></div> </main><!-- #main --> </div><!-- #primary --> </div><!-- .row/not-found --> </div><!-- #content --> </div><!-- .container/.main-content --> <footer id="colophon" class="site-footer" itemscope itemtype="http://schema.org/WPFooter"> <div class="site-info"> <div class="container"> <span class="copyright">Copyright © 2022 Labcorp All rights reserved.</span> </div> </div> </footer><!-- #colophon --> <button aria-label="go to top" id="blossom-top"> <span><i class="fa fa-angle-up"></i>TOP</span> </button> </div><!-- #page --> <script data-cfasync="false" src="/cdn-cgi/scripts/5c5dd728/cloudflare-static/email-decode.min.js"></script><script type='text/javascript' src='https://ddblog.labcorp.com/wp-content/themes/blossom-feminine-pro/js/all.min.js?ver=5.6.3'></script> <script type='text/javascript' src='https://ddblog.labcorp.com/wp-content/themes/blossom-feminine-pro/js/v4-shims.min.js?ver=5.6.3'></script> <script type='text/javascript' src='https://ddblog.labcorp.com/wp-content/themes/blossom-feminine-pro/js/sticky-kit.min.js?ver=1.1.3'></script> <script type='text/javascript' src='https://ddblog.labcorp.com/wp-content/themes/blossom-feminine-pro/js/owl.carousel.min.js?ver=2.2.1'></script> <script type='text/javascript' src='https://ddblog.labcorp.com/wp-content/themes/blossom-feminine-pro/js/owl.carousel.aria.min.js?ver=2.0.0'></script> <script type='text/javascript' src='https://ddblog.labcorp.com/wp-content/themes/blossom-feminine-pro/js/jquery.matchHeight.min.js?ver=0.7.2'></script> <script type='text/javascript' src='https://ddblog.labcorp.com/wp-content/themes/blossom-feminine-pro/js/wow.min.js?ver=1.1.3'></script> <script type='text/javascript'> /* <![CDATA[ */ var bfp_data = {"lightbox":"","auto":"","loop":"","speed":"3000","animation":"fadeOut","child":"default","sticky":"","sticky_widget":"","header":"eight","url":"https:\/\/ddblog.labcorp.com\/wp-admin\/admin-ajax.php","rtl":""}; /* ]]> */ </script> <script type='text/javascript' src='https://ddblog.labcorp.com/wp-content/themes/blossom-feminine-pro/js/custom.min.js?ver=2.3.3'></script> <script type='text/javascript'> /* <![CDATA[ */ var bfp_ajax = {"url":"https:\/\/ddblog.labcorp.com\/wp-admin\/admin-ajax.php","startPage":"1","maxPages":"2","nextLink":"https:\/\/ddblog.labcorp.com\/molecule-type\/biomarkers\/page\/2\/","autoLoad":"load_more","loadmore":"Load More Posts","loading":"Loading...","nomore":"No More Post","layouts":"two-col-right","plugin_url":"https:\/\/ddblog.labcorp.com\/wp-content\/plugins"}; /* ]]> */ </script> <script type='text/javascript' src='https://ddblog.labcorp.com/wp-content/themes/blossom-feminine-pro/js/ajax.min.js?ver=2.3.3'></script> <script type='text/javascript' src='https://ddblog.labcorp.com/wp-includes/js/wp-embed.min.js?ver=5.4'></script> <script type="text/javascript"> if(typeof _satellite !== "undefined"){ _satellite.pageBottom(); } </script> </body> </html>